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Year : 2019  |  Volume : 10  |  Issue : 4  |  Page : 225-228

Idiopathic hepatic granulomatosis: A challenging case of fever of unknown origin

Department of Internal Medicine, BLK Super Speciality Hospital, New Delhi, India

Correspondence Address:
Dr. Vivek Pal Singh
Department of Internal Medicine, BLK Super Speciality Hospital, Pusa Road, New Delhi - 110 005
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/INJMS.INJMS_66_19

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For any physician, fever of unknown origin (FUO) is an enigmatic problem, while being equally frustrating. It tests the limits of patience of both the physician and the patient. While the majority of such cases end up being of infective etiology, the rest are attributable to noninfectious inflammatory disorders (NIIDs) and neoplasms. Among the NIIDs, most turn out to be connective tissue disorders (CTDs). CTDs are commonly known to have granulomas on histopathology. However, hepatic granulomas are rarely encountered. We present a case of FUO in an elderly urban North Indian businessman who after thorough workup was diagnosed with idiopathic hepatic granulomatous disease. Response to disease-modifying therapy was rewarding.

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