Figure 1: Possible mechanisms involved in the pathogenesis of periodontitis in diabetes. AGEs: Advanced glycation end products, ECM: Extracellulara matrix, PMNs: Polymorphonuclear neutrophils, IL: Interleukins, TNF α: Tumor necrosis factor-α, LPS: Lipopolysaccharides, PGE2: Prostaglandin E2, ROS: Reactive oxygen species, RANKL: Receptor activator of nuclear factor kappa-B ligand, OPG: Osteoprotegrin